HEMATOPOIESIS IN PANTOTHENIC ACID-DEFICIENT RATS

Hematopoiesis in pantothenic acid-deficient rats.

Metabolic response to a pantothenic acid deficient diet in humans.

The responses of human subjects to a low pantothenic acid test diet and to the same diet supplemented with 10 mg pantothenic acid daily for 63 days were observed. Pantothenic acid in urine and blood and also nitrogen balance were used as criteria for nutritional evaluation. The mean daily urinary pantothenic acid excretion decreased from 3.05 to 0.79 mg in male adult subjects fed a pantothenic ...

Effects of pantothenic acid on testicular function in male rats.

Pantothenic acid (PaA) is a water-soluble vitamin required to sustain various physiological functions in animals. The physiological roles of PaA on testicular function, in particular, testicular endocrinology and sperm mortility, were investigated in rats. Male rats at 3 weeks of age were fed a PaA-free diet or a 0.0016% PaA diet (control) for 7 weeks. Total body weight, as well as the weights ...

The effect of pantothenic acid deficiency on acetylation in rats.

The ability of normal and pantothenic acid-deficient rats to acetylate a foreign substance was compared by injection of p-aminobenzoic acid (PAB) and the subsequent measurement of the acetylated PAB excreted. Young male rats weighing around 100 gm. or mature rats averaging over 300 gm. were used in various experiments. Those selected for pantothenate deficiency were given a purified diet free o...

Markedly perturbed hematopoiesis in acid ceramidase deficient mice.